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Off-label use for hyperbilirubinemia: Phenobarbital induces glucuronyl transferase and hepatic bilirubin-binding Y-protein to lower serum bilirubin concentrationsKeep track of Closely (one)somatropin will lower the level or outcome of phenobarbital by impacting hepatic/intestinal enzyme CYP3A4 metabolism.Use in Pediatric People. Phenobarbital has a